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Discover the world’s first 3D Course Syllabus: "Cellular & Molecular Biology of Cancer"
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  • The world's first 3D course syllabus: "Cellular & Molecular Biology of Cancer."
  • 10 subjects with 127 engaging 3D animation videos + 127 Interactive Self-Evaluation Tests + Course Exams for each subject + Full Syllabus Final Exam + Certificate of the Course.
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    01. MOLECULAR GENETICS OF CANCER

    DNA alterations can give rise to mutations in proteins that play key roles in the proliferation and the survival of cells, processes that are essentially altered in cancer. Understand the replication, transcription and translation of the genetic material, as well as the role of epigenetics, non-coding RNAs, tumor viruses, mechanisms for repairing errors in the DNA and microsatellite instability. You’ll see why they are all pivotal in identifying different molecular processes that cause these mutations.

    13 3D Animation videos

    13 Interactive Self-Evaluation Tests

    Exam

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    02. CELL CYCLE AND SENESCENCE

    The cell cycle is a highly regulated and complex process. Alterations in proteins at its various checkpoints can provoke uncontrolled division of the cell. Explore each of the phases of the cycle and the specific role of its key proteins, such as the tumor suppressors pRb, p21, p16 and p53, as well as the importance of telomerase activity in avoiding cellular senescence. Acquire a thorough understanding of some of the processes involved in the development of tumors.

    10 3D Animation videos

    10 Interactive Self-Evaluation Tests

    Exam

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    03. CELL PROLIFERATION AND CANCER

    Cell proliferation is under controlled balance and regulated by many different growth factors, hormones, transcription factors and other proteins that interconnect the different signaling pathways. Go in-depth into specific mutations in the different components of these pathways, the metabolic changes they cause and the ability that cancer cells acquire to overcome growth restriction. Finally, discover the keys to understanding the origin of the high rates of proliferation found in cancer cells.

    13 3D Animation videos

    13 Interactive Self-Evaluation Tests

    Exam

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    04. PROGRAMMED CELL DEATH

    Apoptosis, necrosis and autophagy are three mechanisms that cause cell death and that can be abnormal in tumor cells. Study the activation of apoptosis, the conditions that trigger necrosis in a tumor and the way autophagy changes in specific cell types from a recycling process to one that provides nutrients to cancer cells and promotes cell death. See how the interrelationship between the different proteins of these three mechanisms is essential in acquiring a comprehensive vision of the way cancer cells are able to manage cell death.

    8 3D Animation videos

    8 Interactive Self-Evaluation Tests

    Exam

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    05. IMMUNE SYSTEM AND CANCER

    In the initial stages of the carcinogenic process, the body’s immune system fights the tumor. However, in the more advanced stages, tumor immunosuppression arises and some immune cells become allies of the tumor cells. Learn about the molecular mechanisms involved, specifically that of the membrane receptors and cytokines, and gain the necessary knowledge to understand this paradoxical immune activity in cancer.

    19 3D Animation videos

    19 Interactive Self-Evaluation Tests

    Exam

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    06. ANGIOGENESIS

    Angiogenesis is a key process in tumor progression as it ensures nutrient supply and favors cell dissemination. Study the specific cells and proteins that are associated with tumor angiogenesis and understand its development, how it differs from physiological vascularization and the various signaling pathways involved in the migration of endothelial cells and the establishment of new vessels, such as the vascular endothelial growth factor and the neuropilin pathways.

    15 3D Animation videos

    15 Interactive Self-Evaluation Tests

    Exam

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    07. LOCAL INVASION AND METASTASIS

    Understand transformation, local invasion, migration through the bloodstream and the survival strategies that tumor cells develop in the context of a metastatic process. Also learn about factors such as exosomes, which allow tumors to prepare their metastatic destination, or cells such as metastasis-associated macrophages which collaborate in tumor extravasation and survival in newly colonized tissue. Acquire a deeper insight of the mechanisms involved in tissue-specific metastasis.

    23 3D Animation videos

    23 Interactive Self-Evaluation Tests

    Exam

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    08. IMMUNOTHERAPY

    Cancer immunotherapy involves or uses components of the immune system. It provides different strategies to fight tumors, such as the application of monoclonal antibodies directed against tumor antigens and immune checkpoints, or the stimulation of the immune cells, either directly or by means of tumor antigens. Discover its mechanisms of action at the molecular level and gain deeper knowledge of the cellular level and the possibilities of immunotherapy in treating cancer.

    13 3D Animation videos

    13 Interactive Self-Evaluation Tests

    Exam

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    09. CHEMOTHERAPY

    Chemotherapy works by stopping or slowing the growth of cancer cells. Learn about chemotherapy treatments and understand their mechanisms of action on genetic material and on the proteins that interact with them, such as microtubules during mitosis and topoisomerases in the replication process. See how these treatments can also interfere with DNA repair mechanisms and nucleotide synthesis.

    04 3D Animation videos

    04 Interactive Self-Evaluation Tests

    Exam

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    10. TARGETED AND HORMONAL THERAPY

    Go in depth with the specific therapies directed at hormones, receptors and particular proteins in order to comprehend the tumorigenic processes in which these molecules play a role, such as the cell cycle, intracellular signaling pathways and angiogenesis. Finally, understand how targeted therapies are able to effectively readjust these processes in a suitable cancer context.

    09 3D Animation videos

    09 Interactive Self-Evaluation Tests

    Exam